Atripla (Efavirenz)

Atripla (Efavirenz)


Atripla (Efavirenz, Emtricitabine, Tenofovir) is an antiviral drug. The action of active components Efavirenz, Emtricitabine, Tenofovir is focused upon prevention of human immunodeficiency virus (HIV) reproduction in the body. The drug is designed to treat HIV, causing acquired immunodeficiency syndrome (AIDS). The drug does not help to recover from HIV or AIDS.

Atripla is supplied as: Efavirenz 600mg / Emtricitabine 200mg / Tenofovir 300mg.

Indications for Atripla use


  • Treatment of HIV-1 infection in adults, both in monotherapy and combined therapy with other antiviral drugs.

Contraindications to Atripla


  • Allergy to the drug components;
  • Pregnancy
Use with any of the following drugs:
  • Triazolam (Halcion) or Midazolam (Versed);
  • Cisapride (Propulsid);
  • St. John's wort;
  • Vriconazole (Vfend);
  • ergot derivatives (such as Ergonovine (Ergotrate), and others);
  • Lamivudine (Combivir, Epivir, Epzicom, or Trizivir);
  • or any other drug, containing Efavirenz, Emtricitabine and Tenofovir (such as Emtriva, Sustiva, Viread or Truvada).
Side Effects of Atripla when immediate medical assistance is required:
  • Allergy (difficulty breathing, swelling of the face, lips, tongue or throat).
  • Lactacidosis (a life-threatening lactic acid accumulation in the body) with such symptoms as: muscle pain or weakness, numbness or cold hands and feet, difficulty breathing, stomach pain, nausea and vomiting, rapid or irregular heartbeat, drowsiness or weakness /fatigue.
  • Dangerous liver disorder with such symptoms as nausea, stomach pain, fever, cloudy urine, putrid stool, yellow skin and eyes (hepatitis).
Alcohol may worsen the drug side effects.
Therapy with Atripla does not guarantee that the virus will not be transmitted to others.

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