Sustiva (Efavirenz)

Sustiva (Efavirenz)


Sustiva is an antiviral drug, non-nucleoside reverse transcriptase inhibitor. This drug is used in treatment of HIV and Hepatitis B. It delays the virus distribution into healthy cells and inhibits immunodeficiency virus development in infected cells.

Sustiva is used in treatment of hepatitis B and reduces the virus level in the body.

Sustiva is supplied as tablets of Cipla 200 mg and 600mg.

Indications for Sustiva use


The indications for Sustiva: HIV infection in combined therapy, chemoprophylaxis of HIV infection after contact with infected HIV-materials (sex with HIV-infected partner, punctures and cuts operating with HIV-contaminated instruments), type B and C hepatitis.

Contraindications to Sustiva


Contraindications to Sustiva: hypersensitivity, pregnancy, breast-feeding. Extra care should be taken in hepatic and/or renal failure, alcohol abuse, drug addiction, encephalopathy, and in children under 3 years old, with body weight less than 13 kg.

Side effects of Sustiva


  • nausea,
  • vomiting,
  • drowsiness,
  • dizziness,
  • depression,
  • mental disorders,
  • rash,
  • pruritus,
  • hematuria,
  • nephrolithiasis,
  • increased blood cholesterol level.
Sustiva provides protection of healthy cells from virus infection and delay viral DNA replication in the infected DNA cells. The drug is used in combined antiretroviral therapy.

The drug is taken orally once a day at bedtime. The daily dose for children weighing 13-15 kg is 200mg, 15-20 kg - 250mg, 20-25 kg - 300mg, 25-32,5 - 350mg, 32,5-40 - 400mg, more 40 kg - 600mg.

Any other drugs are forbidden during the treatment without prior doctor's consent. A fat-low diet is recommended.

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